![]() This elevation occurred on 2 separate occasions, which distinguishes our case from other published literature. Our case report describes INR elevations in a patient previously stable on warfarin after ingestion of cranberry juice cocktail daily for several days. ![]() There have been several case reports of cranberry juice or cranberry sauce potentiating the effects of warfarin by elevating the INR however, clinical trials evaluating this interaction have failed to demonstrate a significant effect on an INR. Warfarin is the most commonly used anticoagulant for chronic therapy. An objective causality assessment revealed the interaction was highly probable. During both of the elevated INR episodes, no other factors were identified that would have resulted in an elevated INR, such as drug, herbal, disease, or other food interactions. Filtered Water, High Fructose Corn Syrup, Cranberry Juice From Concentrate (Filtered Water, Cranberry Juice Concentrate), Grape Juice From. Her INR 7 days after resuming the weekly dose of warfarin 56 mg was 3.2. Her INR after holding warfarin for 3 days was 1.86. Drinking cranberry juice (unsweetened cranberry juice) aids digestion and supports renal and cardiovascular health and more. At a subsequent visit, after drinking approximately 2 quarts (1893 mL) of cranberry juice cocktail daily for 3-4 days, her INR had increased to 6.5. For the next 3 months, while taking warfarin 56 mg per week, her average INR was 2.1, with a range of 1.4-2.5. Her INR 14 days later without cranberry juice cocktail consumption was 2.3. Her INR increased to 4.6 after drinking approximately 1.5 quarts (1420 mL) of cranberry juice cocktail daily for 2 days. During the 4 months prior to the incident INR, her average INR was 2.0, with a range of 1.6-2.2, while taking the same weekly dose of warfarin. This image has been modified.To report a case of warfarin-cranberry juice interaction, which resulted in an international normalized ratio (INR) elevation on 2 separate occasions.Ī 46-year-old female was receiving a total weekly dose of 56 mg of warfarin. References may also be found at the back of his books. Sources for each video listed can be found by going to the video’s page and clicking on the Sources Cited tab. ![]() The information on this page has been compiled from Dr. More proof that it’s nearly always best to give preference to whole foods. There’s some indication that cranberry products, in either juice, cranberry extract, or tablet form, may have infection-fighting properties, but the benefit is small. Extracts concentrating individual components fail to match the anticancer effects of the cranberry as a whole, which of course can’t be patented. Cranberries have long been the focus of interest for their beneficial effects in preventing urinary tract infections (UTIs). Scientists have been unable to pin down the active ingredients involved in cranberries’ special effects. Unfortunately, there have yet to be clinical studies of the effects of cranberries on cancer patients that confirm these findings. Studies have also found that cranberries can be effective in vitro against brain, breast, colon, lung, mouth, ovary, prostate, and stomach cancers. In theory, they could “pull out” metals that accumulate in certain brain areas and may play a role in the development of Alzheimer’s and other neurodegenerative diseases. The researchers suspect the active ingredient may be a class of powerful brain-accessing antioxidants called polyphenols, readily found in cranberries.īeyond their antioxidant activity, polyphenols have been shown to protect nerve cells in vitro by inhibiting the formation of the plaques and tangles that characterize Alzheimer’s brain pathology. ![]() As a group, they average nearly 10 times more antioxidants than other fruits and vegetables (and exceed 50 times more than animal-based foods).Ī study that followed nearly two thousand people for about eight years found that people who drank fruit and vegetable juices regularly appeared to have a 76 percent lower risk of developing Alzheimer’s disease. ![]() My Daily Dozen calls for a minimum of one daily serving of berries, such as cranberries, in addition to three daily servings of other fruits.īerries are the healthiest fruits, in part due to their respective plant pigments, and are second only to herbs and spices as the most antioxidant-packed food category. The Global Burden of Disease Study, the largest analysis of risk factors for death and disease in history, determined not eating enough fruit was among the worst aspects of our diet. ![]()
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